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Juul A, Bang P, Hertel NT, Main K, Dalgaard P, Jrgensen K, Mller J, Hall K, Skakkebaek NE

If needed for a clear medical indication (such as treating pellagra in a pregnant patient), niacinamide can be used with caution, but unnecessary high-dose B supplementation is avoided in pregnancy

Stability: Chemically stable at room temperature when protected from direct light and moisture

The biological plausibility of AOD9604s cartilage-regenerating effects is further supported by insights from conditions such as acromegaly, where excess GH leads to abnormally thick cartilage due to elevated local IGF-1 production

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